Customization: | Available |
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Application: | Human Medicine |
Usage Mode: | For oral administration |
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Name | Cefixime |
Melting point | 218-225°C |
Drug type | Beta-lactam antibiotics, cephalosporins |
Indication | For streptococcus (except enterococcus), pneumococcus, gonococcus, Catarrania, Escherichia coli, Klebsiella, Serrella, Proteus and influenzae caused by bacterial infectious diseases. |
Common dosage form | Tablets, capsules, granules |
Medicine Interactions | 1. It has a synergistic antibacterial effect on certain sensitive strains when used in combination with aminoglycoside antibiotics. 2. It has been reported that aspirin may increase the plasma concentration of cefixime. 3. Combined use with aminoglycosides or other cephalosporins will increase nephrotoxicity. 4. Combined use with strong diuretics such as furosemide can enhance nephrotoxicity. 5. There may be mutual antagonism with chloramphenicol. 6. Probenecid can prolong the excretion of cefixime and increase the blood concentration. |
Mechanism | The antibacterial mechanism of cefixime is similar to that of other third-generation cephalosporins. It inhibits cell wall synthesis of dividing bacterial cells by binding to one or more penicillin-binding proteins (PBPs). PBPs are located on the bacterial cytoplasmic membrane and may be catalytic enzymes for the Chemicalbook in the final stage of bacterial cell wall synthesis. The effect of this product is to cause bacteria to form a defective cell wall that is unstable to osmotic pressure, thereby exerting an antibacterial effect. Different strains have their own unique PBPs. The different affinities of cefixime to different PBPs are the main factors affecting its antimicrobial spectrum activity. |
Precautions | 1. Due to the possibility of shock, a thorough medical history should be obtained before administration. 2. In order to prevent the emergence of drug-resistant strains, in principle, the sensitivity should be confirmed before using this product, and the dose should be controlled to the minimum dose required to control the disease. 3. For patients with severe renal dysfunction, since the concentration of the drug can be maintained in the blood, the dosage should be appropriately reduced according to the renal function status, and the dosing interval should be appropriately increased. |
drug-drug interactions | 1. Carbamazepine: When combined with this product, the level of carbamazepine may increase. If combined use is necessary, the concentration of carbamazepine in the plasma should be monitored. 2. Warfarin and anticoagulant drugs: increase the prothrombin time when combined with this product. 3. This product may cause intestinal bacterial disorder and inhibit vitamin K synthesis. |
1.We have a professional and efficient team that can meet your various needs.
2.Have rich knowledge and sales experience in chemical products, and have in-depth research on the use of products and how to maximize their effects.
3.The system is sound, from supply to production, packaging, quality inspection, after-sales, and from quality to service to ensure customer satisfaction.
4.Price advantage. On the premise of ensuring quality, we will give you the best price to help maximize customers' interests.
5.Transportation advantages, air, sea, land, express, all have dedicated agents to take care of it. No matter what transportation method you want to take, we can do it.
After Sales Serve
Before shipping: Send the estimated shipping time, estimated arrival time, shipping advice, and shipping photos to the customer in advance.
During transportation: Update tracking information timely.
Arrival at destination: Contact the customer after the goods arrive at the destination.
After receiving the goods: Track customer's goods packaging and quality.
FAQs:
1. Can I get samples?
Of course, we provide our customers free samples, but you need to pay the shipping cost on your own.
2. What are the payment terms?
For payment terms, we accept Bank Account, West Union, L/C, T/T, D/P and so on.
3. How about the packaging?
We provide the usual types of packages for our customers. If you need, we can also customize packages as you required.
4. How about the shipping costs?
We provide air, sea and land transportation. According to your order, we will choose the best way to transport your goods. Shipping costs may vary because of the different shipping ways.
5. What are the delivery time?
We will arrange production immediately as soon as we accept your deposit. For small orders, the delivery time is approximately 3-7 days. For large orders, we will start production as soon as possible after the contract is signed, the appearance of the product is confirmed, the packaging is made and your approval is obtained.
6. Do you have the after-sales service?
Yes, we have. We have seven systems to guarantee your goods produce smoothly. We have Supply System, Production Management System, QC System, Packaging System, Inventory System, Inspection System Before Delivery and After-Sales System. All of them are applied to ensure your goods arriving at your destination safely. If you have any questions, please feel free to contact us.